来自MSN4 个月
New study challenges longstanding assumption about the cause of the genome's most common ...deamination, is about twice as likely to happen when a cytosine is chemically tagged by the addition of a molecule known as a methyl group to create 5-methylcytosine, which occurs in DNA at so ...
Mutations can occur when adenine is altered or mismatched with other bases. For example, the deamination of adenine can lead to the formation of hypoxanthine, which can pair with cytosine instead of ...
DNA and RNA, however, are prone to degradation particularly when stored incorrectly. They are especially sensitive to depurination, deamination, depyrimidination, hydrolytic cleavage, nuclease ...
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