The deamination reactions (30 µl total volume), containing GST–AID (200 ng = 4 pmol), RNase (1 µg) and gapped DNA substrate (500 ng = 100 fmol) dissolved in a reaction buffer (10 mM Tris-HCl ...

We conclude that transcription targets the DNA deamination activity of AID to dsDNA by generating secondary structures that provide ssDNA substrates. Nature - Transcription-targeted DNA ...

These four DNA bases – adenine (A), cytosine (C), guanine (G) and thymine (T) – form specific pairs that are always supposed to be matched with each other: A with T, and G with C.

The team found that the noncoding RNA contained two loops, a donor loop that could recognize IS110’s own DNA, and a target loop able to recognize DNA at an insertion site somewhere in the genome.

Most humans alive today can trace a very small percentage of their DNA to Neanderthals. However, Neanderthal DNA is slightly more abundant in the genomes of certain populations.

Researchers have finally deciphered a complete human genetic instruction book from cover to cover. The completion of the human genome has been announced a couple of times in the past, but those ...

The DNA of 10 families exposed to the ’80s violence and 22 families to the 2011 conflict was compared to the genetic material of 16 families who left Syria before 1980, avoiding decades of unrest.

A long history of mercantile trade along the eastern shores of Africa left its mark on the DNA of ancient Swahili people. A new analysis of centuries-old bones and teeth collected from six burial ...