Magnesium contact ions stabilize the macromolecular structure of transfer RNA Date: December 9, 2020 Source: Forschungsverbund Berlin Summary: In cells transfer RNA (tRNA) translates genetic ...

We have developed a new method, tRNA-Map, that can analyze RNA-related enzymes using next-generation DNA sequencing. We analyzed tRNA m1A22 methyltransferase (TrmK) using tRNA-Map. Mutation ...

High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq. Molecular Cell , 2021; DOI: 10.1016/j.molcel.2021.01.028 Cite This Page : ...

"The NMR revealed that the hydrogen bonds holding the tRNA together are weakened in these excited states," said Royer. "The small-angle X-ray scattering at high pressure, which we did at CHESS ...

A groundbreaking study conducted by a research team from Kumamoto University has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings ...

More than 10% of all genetic diseases are caused by mutations that prevent cells from making fully formed proteins. An experimental therapy that uses suppressor transfer RNA (tRNA) could help ...