Magnesium contact ions stabilize the macromolecular structure of transfer RNA Date: December 9, 2020 Source: Forschungsverbund Berlin Summary: In cells transfer RNA (tRNA) translates genetic ...

The wiring diagram and its supporting files amount to 1.6 petabytes’ worth of data. The map traces more than 2.5 miles (4 kilometers) of tangled-up axons, the fibers that serve as the “wiring ...

Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain to date using tissue from a part of a mouse's cerebral cortex involved in vision, an achievement ...

High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq. Molecular Cell , 2021; DOI: 10.1016/j.molcel.2021.01.028 Cite This Page : ...

We have developed a new method, tRNA-Map, that can analyze RNA-related enzymes using next-generation DNA sequencing. We analyzed tRNA m1A22 methyltransferase (TrmK) using tRNA-Map. Mutation ...

A groundbreaking study conducted by a research team from Kumamoto University has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings ...

In 1982, researchers finally attempted to use sup-tRNAs against a disease. 6 At the University of California, San Francisco, geneticist and hematologist Yuet Wai Kan wanted to treat a version of the ...

More than 10% of all genetic diseases are caused by mutations that prevent cells from making fully formed proteins. An experimental therapy that uses suppressor transfer RNA (tRNA) could help ...