More than 33,000 glycosyltransferases have been identified. Structural studies, however, have only revealed two distinct glycosyltransferase (GT) folds, GT-A and GT-B. Here we report a 1.34-Å ...

Voltage-gated sodium channels (VGSCs) are responsible for transmembrane (TM) sodium ion conduction and, in eukaryotes, for electrical signalling in excitable cells 1. In humans, mutations in different ...