We have studied cytoskeletal architectures of isolated mitotic apparatus from sea urchin eggs using quick-freeze, deep-etch electron microscopy. This method revealed the existence of an extensive ...

Cytoplasmic dynein is a minus end–directed molecular motor in the AAA+ family of ATPases that couples ATP hydrolysis to the generation of mechanical force. In an effort to identify new cellular ...

Flagella and cilia are critical cellular organelles that provide a means for cells to sense and progress through their environment. The central component of flagella and cilia is the axoneme, which ...