In neurons, neurotransmitter-containing secretory vesicles are transported along microtubules from the proximal golgi apparatus to the distal pre-synaptic membrane, and various signalling molecules ...

本研究揭示了核膜KASH蛋白UNC-83通过可变剪接产生的不同亚型（UNC-83a/b与UNC-83c）差异调控kinesin-1（驱动蛋白-1）活性的新机制 ...

Regulation of organelle transport by molecular motors along the cytoskeletal microtubules is central to maintaining cellular functions. Here, we show that the ubiquitous tau-related ...

Cytoplasmic dynein is a homodimenc AAA+ motor that transports a multitude of cargos toward the microtubule minus end. How the two catalytic head domains interact and move relative to each other during ...