Chikungunya病毒(CHIKV)包膜蛋白E1-E2复合物被新型小分子抑制剂靶向,通过拆分化合物1的立体异构体发现S型活性更高(EC50=6 μM ...
In all organisms, innate immune pathways sense infection and rapidly activate potent immune responses while avoiding inappropriate activation (autoimmunity). In humans, the innate immune receptor ...