Microvascular endothelial dysfunction is an early or inductive event that occurs in the development of cardiovascular diseases and associated organ damage. The endothelium is composed of a single ...

Sepsis is a life-threatening condition that often leads to ARDS, characterized by widespread inflammation and vascular injury. This study identifies lactate-driven lysine lactylation (Kla) as a ...

A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...