Estrogen agonists/antagonists, also referred to as selective estrogen-receptor (ER) modulators (SERMs), are one group of compounds that are being used or evaluated for both osteoporosis prevention ...

Collins and Webb reply—In no way did we intend to give the impression that estrogen receptors on the surface of plasma membranes or intracellular coupling was a new concept. Our News & Views ...

Newly discovered estrogen receptor-dependent signaling pathways demonstrate that estrogen functions in the cytosol as well as in the nucleus. The classic estrogen receptor signaling pathway occurs ...

Their study, published recently in Nature, focuses on what is known as the estrogen receptor, a protein linked in previous research to the development of roughly 70% of all breast tumors.

If the trial is successful, the firm's complete estrogen receptor antagonist would complement its other biomarker-driven breast cancer assets.

The researchers found that imlunestrant prolonged progression-free survival (PFS) when compared to standard care in patients with ESR1 mutations, but there was no PFS benefit observed in the overall ...

which do not rely on estrogen receptors for tumor growth. Conversely, anti-estrogen therapies inhibited estrogen receptor ...

The Fatima bint Mubarak Center at Cleveland Clinic Abu Dhabi, part of the M42 group, becomes the first center in the GCC ...

Raloxifene can be classified as a second-generation SERM. A SERM interacts with estrogen receptors, functioning as an estrogen agonist in some tissues and an antagonist in other tissues.

Live webcasts of these presentations will be available in the Events and Presentations section of Olema’s investor relations website at ir.olema.com. The webcasts will be archived for at least 30 days ...