Please use one of the following formats to cite this article in your essay, paper or report: APA. AstraZeneca. (2020, January 30). Targeting the Estrogen Receptor in Breast Cancer.

In this section, we review key current topics in the management of estrogen receptor–positive breast cancer. We review therapeutic options that may reduce the risk of late relapse, how to optimally ...

Panelists discuss the EMBER-3 trial, which evaluated single-agent oral selective estrogen receptor degrader (SERD) ...

HER2 tumor marker tests are used to determine whether breast cancer is HER2 positive or negative. A person is a candidate for ...

Estrogen, the major female ovarian hormone, can trigger nerve impulses within milliseconds to regulate a variety of physiological processes. At Baylor College of Medicine, Louisiana State University ...

Vepdegestrant is an oral proteolysis-targeting chimera (PROTAC) estrogen receptor (ER) degrader that directly harnesses the ubiquitin–proteasome system.In this phase 3, open-label, randomized ...

Risk Factors. Endogenous Hormones: High lifetime exposure to estrogen and progesterone increases the risk of hormone receptor positive breast cancer. Exogenous Hormones: A study by Salagame et al ...

Estrogen is also theorized, says Javaid, to contribute to the onset of mild cognitive decline commonly associated (affecting up to 62% of women) with perimenopause and menopause, like brain fog ...

Researchers in Japan found that estrogen produced within the brain, called neuroestrogen, suppresses appetite and reduces body weight in mice by enhancing MC4R expression. The study also showed ...

The researchers propose that interacting with the ER-alpha-Clic1 complex enables estrogen to trigger fast neuronal responses through Clic1 ion currents. The study appeared in Science Advances .