The modulation of neuronal glutamate receptors by phosphorylation is considered to be critical for synaptic plasticity. In particular, altering NMDA–type glutamate receptor properties by ...

Mutated variants of a particular ion channel cause difficult-to-treat epilepsy. A study published in the journal Nature now shows that a commonly used anesthetic drug, propofol, can restore the ...

Two mutations identified in individuals with developmental and epileptic brain disease can be traced back to the same ion channel. Researchers have now elucidated how both independent mutations affect ...