POLG-related diseases disrupt the function of the mitochondria, or "powerhouses" of the cell — starving them of energy.

Single-cell transcriptomics has revolutionized the study of cellular diversity and function by enabling gene expression ...

University of Illinois at Urbana-Champaign researchers have developed a CRISPR-based diagnostic tool capable of detecting ...

For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the ...

Scientists found that fast-evolving DNA shaped human brain development but might also increase risks for mental disorders.

Georgia State University researchers used simulations to study DNA repair mechanisms, focusing on the pre-incision complex in ...

A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...

The applied physicist explains how the structure of 52,000-year-old genes hint at the biology of an extinct animal ...

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review ...

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury. This review sheds light on ...