POLG-related diseases disrupt the function of the mitochondria, or "powerhouses" of the cell — starving them of energy.

Sunburns and aging skin are obvious effects of exposure to harmful UV rays, tobacco smoke and other carcinogens. But the ...

Single-cell transcriptomics has revolutionized the study of cellular diversity and function by enabling gene expression ...

For the Liu Lab, necessity is truly the mother of invention.The researchers were examining how the 3D organization of the ...

Scientists found that fast-evolving DNA shaped human brain development but might also increase risks for mental disorders.

Georgia State University researchers used simulations to study DNA repair mechanisms, focusing on the pre-incision complex in ...

A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant ...