To analyze next-generation sequencing data, multivariate functional linear models are developed for a meta-analysis of multiple studies to connect genetic variant data to multiple quantitative traits ...

The identification of evolutionarily constrained sequences is an unbiased approach for finding functional sequences in genomes. However, their identification is strongly affected by upstream analyses.

Single-cell functional analysis enables scientists to examine the unique characteristics of each cell within organs, tissues, and cell cultures. Unlike bulk-cell analysis, single-cell analysis allows ...