A new method can capture detailed information about all four phases of the cell cycle in real time using fluorescent proteins. Michael Lin was always curious about cell biology, but he became ...

J. Gautier, M.J. Solomon, R.N. Booher, J.F. Bazan, M.W. Kirschner, "cdc25 is a specific tyrosine phosphatase that directly activates p34 cdc2," Cell, 67:197-211, 1991. Jean Gautier (Station Zoologique ...

Nobody wants to be average. But for a long time, scientists have found it convenient to think of bacterial cells as just that: "average." Researchers have traditionally relied on population-level ...

"We had previously demonstrated that the p53 gene product--the most commonly mutated gene in human cancer--controls cell-cycle arrest in response to damage," says Kastan. In this paper the authors ...

The p53 gene is extremely important in cell biology as its role is to regulate the cell cycle and halt the formation of tumors, leading to its nickname the “tumor suppressor gene.” However, previous ...