Computational prediction of gene structure is crucial for interpreting genomic sequences. But how do the algorithms involved work and how accurate are they? Expression-based systems that use only ...

The question “What is a gene?” has bothered geneticists for fifty years. Recent work with a small bacterial virus has shown how to split the gene and make detailed maps of its internal structure ...

Ionising radiation includes gamma rays, X-rays and ultraviolet rays. The greater the dose of radiation a cell gets, the greater the chance of a mutation. Mutations could cause different genes to ...

When a gene is to be expressed ... Peptide bonds form between the adjacent amino acids to finalise the structure.

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Danon disease is a rare but serious cardiomyopathy that drastically reduces life expectancy. Male patients infrequently live ...