UCSF researchers identified 30 transcription factors that reverse age-related gene expression in fibroblasts. Using CRISPR to adjust these regulators restored youthful metabolism and growth in old ...

The establishment and maintenance of neuronal identity are critically dependent on a finely tuned interplay between transcription factors and the epigenetic landscape. Central to this network is the ...

The YABBY gene family comprises plant‐specific transcription factors that play pivotal roles in defining lateral organ polarity and promoting organogenesis in seed plants. These genes ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

Floral scent is a defining trait for many ornamental plants, yet the genetic logic behind fragrance production often remains ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells. How genes are turned on ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...