The ideal HIV vaccine would elicit humoral responses effective against a broad spectrum of primary HIV strains but immunogens capable of generating such antibodies in humans have been difficult to ...

Since HIV’s discovery in the 1980s, scientists have come a long way in understanding the different steps required for its assembly and maturation. Researchers knew, for instance, that HIV wraps its ...

Researchers from the California Institute of Technology and collaborating institutions have developed a novel HIV vaccine candidate, a new germline-targeting Env SOSIP trimer called 3nv.2, that is ...

To mark the occasion of World AIDS Day, Dr. Madeleine Durand and Andrés Finzi are working to reduce chronic inflammation and the risk of comorbidities in people living with HIV. The human ...

HIV has proven a hard target for vaccine design. The most promising approach, germline-targeting (GT), proposes a series of immunizations: a first shot to activate inexperienced B ...

Researchers at Fred Hutchinson Cancer Center, led by Dr. Julie McElrath, Director of the Vaccine and Infectious Disease Division, have found a new way to train our immune system to make antibodies ...

New HIV vaccines have shown promise in studies with lab animals and human volunteers, pointing to a potential way of preventing the lifelong viral disease. These experimental vaccines are built upon ...

In what may be one of the most important HIV research breakthroughs in years, scientists have discovered a strikingly powerful antibody, called 04_A06, that is able to neutralize nearly all of the ...

The battle against HIV-1, the virus that causes AIDS, has been ongoing for decades. Perhaps one of the most important advances in their understanding and fight against the virus has been the ...