In the past few years, high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) has matured to a true alternative to antibody-based immunoassays in routine therapeutic drug ...

This paper describes a unique Prep-rP-HPLC technique that uses a C-18/C-8 derivatized silica coated with a hydrophobic quaternary ammonium salt or quaternary phosphonium salt that acts as an ...

This short seminar is suitable for all analysts working in HPLC/UHPLC and focuses on the preventable problems that commonly occur with LC columns. The course will help analysts to think about how they ...

The authors review methods for reducing analysis time and increasing throughput that are reliable and maintain data integrity. Performing separations under elevated temperature. The common goal of the ...

HPLC is a widely used tool in peptide and protein purification. One of the challenges in this process is maximizing the lifetime of the bulk media sorbents or prepacked columns, which degrade due to ...

As you reach the end of the run and possibly the conclusion of the workday, you may wonder what to do with the column you have recently used. You might consider whether it should remain attached to ...

Placing UV detectors far away from a chromatographic column can be problematic. The increased extra column volume can cause band broadening, reducing the efficiency of a separation. Also, experiments ...

Method development scientists looking to maximize efficiency and further improve pH stability and column reliability for reverse phase chromatography should look no further, according to Waters ...

The Hi-Plex HPLC columns deliver improved efficiency, lower operating pressures and longer column lifetimes from monodispersed materials. With a range of ligand counter ions for optimum selectivity, ...

The new Thermo Scientific µPAC Neo HPLC Column brings improved column-to-column reproducibility and better protein identification to proteomics researchers MINNEAPOLIS--(BUSINESS WIRE)--ASMS 2022 – ...