本综述系统探讨了造血干细胞(HSC)静息(quiescence)与休眠(dormancy)的分子机制及其在稳态和应激条件下的调控网络,深入解析了细胞周期调控、代谢重编程(如糖酵解和氧化磷酸化)、骨髓微环境信号(如SCF、TPO)以及维生素A代谢(如at-RA、4-oxo-RA)对HSC ...
Haematopoietic progenitors proliferate during infections, even in the absence of peripheral cytopenia. Haematopoietic stem cells (HSCs) respond to both direct and indirect signals during infection.
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