HDL particles are synthesized and catabolized in the liver and intestines ... Apolipoproteins have many roles in lipid metabolism, which are presented in Table II. Table III lists several major ...

The endogenous pathway involves the liver synthesizing lipoproteins. TG and cholesterol ester are generated by the liver and packaged into VLDL particles and then released into the circulation.

More information: Preethi Chandrasekaran et al, The Role of SCAP/SREBP as Central Regulators of Lipid Metabolism in Hepatic Steatosis, International Journal of Molecular Sciences (2024). DOI: 10. ...

A team from Keio University and others said that loneliness without social connections contributes to the development of ...

Background and aims The transcription factor sex-determining region Y-related high-mobility group-box gene 9 (SOX9) plays a critical role in organ development. Although SOX9 has been implicated in ...

The Farese & Walther laboratory investigates cellular lipid and energy metabolism, in particular the mechanisms and physiology of neutral lipid synthesis and storage in lipid droplets. More broadly ...

Patients with metabolic dysfunction-associated steotohepatitis (MASH) who are already taking a glucagon-like peptide-1 receptor agonist (GLP-1RA) could see their liver health improve with the addition ...