BoNT/Aintoxication of LAN5 cells induces massive tRF changes. (A) Experimental design: 2×106 LAN5 cells/well were intoxicated by 10,000 MsLD50/mL BoNT/A, and small RNA-seq profiles from these cells ...

Several bacteria from the Clostridium genus produce botulinum neurotoxins—the most potent biological toxins known—that cause botulism by blocking neurotransmitter release from nerves. Typically, the ...