Striking nucleolar lesions occur in cultured cells after exposure to supranormal temperatures. These lesions appear at 42°C and consist of a loss of the granular ribonucleoprotein (RNP) component and ...

THE nucleolus was first figured in 1781 as a spot in the centre of a round or oval body (the nucleus) in epithelial cells of the eel. Since then it has been described in the nuclei of almost every ...

A team led by Princeton University researchers has developed a tool to peer inside the nucleolus, the cellular compartment responsible for the earliest steps in protein manufacture. This system opens ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

Researchers have shown that an enzyme called RNA polymerase (Pol) II drives generation of the building blocks of ribosomes, the molecular machines that manufacture all proteins in cells based on the ...