Clinicians' ability to diagnose and treat chronic diseases is limited by scientific uncertainty around factors contributing to disease risk. A study published September 2 nd in the open-access journal ...

What determines how long we live—and to what extent is our lifespan shaped by our genes? Surprisingly, for decades, scientists believed that the heritability of human lifespan was relatively low ...

A watercolor artist’s interpretation of the relationship between the human genome and gut mycobiome. Created by Amy Bean, watercolor journalist and mom of first author Emily Van Syoc. Clinicians’ ...

The past decade has delivered landmark advances in human and medical genomics that shape how we understand disease mechanisms ...

Researchers have significantly expanded the catalogue of known human genetic variation. The resulting datasets, shared in two back-to-back publications in the journal Nature, constitute what may be ...

Twenty-two years after the completion of the Human Genome Project, scientists have unveiled the most expansive catalog of human genetic variation ever compiled. Across two new papers published ...

Using a massive exome sequencing database made available through the Exome Aggregation Consortium (ExAC), the international research team identified around 7.4 million genetic variants, providing ...

In the ongoing effort to determine just how much of who we are is preordained by our genetic code, heritability, a statistical measurement of how much variation in a trait can be attributed to genetic ...

A number of studies have highlighted that ethnicity is an important factor influencing the genetic variability of some CYP450 enzymes and that human adaptation could have a role in shaping the genetic ...