PAX6-dependent epithelial differentiation and developmental trajectories of the ocular surface are elucidated through single-cell RNA sequencing of hiPSC-derived ocular organoids. This study provides ...

A new study takes a tour of the history of research into human embryology and development to show the "cycles of attention" that led to major scientific breakthroughs. Analyzing the past sheds light ...

Animal models continue to be a mainstay of basic research and preclinical studies. But since animals such as mice only approximate humans, they may generate findings of limited clinical relevance.

A recent Nature study evaluates post-implantation development in humans using embryo-like models based on genetically unmodified human naïve embryonic stem cells (ESCs). Study: Complete human day 14 ...

Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why ...

The world has now learned of a surprising scientific advance: so-called “synthetic embryos.” Their arrival promises to reveal to medicine previously hidden glimpses into problems of early pregnancy.

Neuroscientists have been trying to understand how the brain processes visual information for over a century. The development of computational models inspired by the brain's layered organization, also ...