A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling. Scientists at The University of Texas Health Science Center at San Antonio have created ...

The reconstitution of a fully functional human immune system in mouse after engraftment of purified hCD34+ hematopoietic cells provide a unique opportunity to assess the efficacy of new oncology drug ...

A new study published in Microbiology Spectrum reports the establishment of a liver-humanized NSG-PiZ mouse model that is fully permissive to hepatitis B virus (HBV) infection. In this model, HBV can ...

Scientists have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19. Scientists at La Jolla Institute for Immunology (LJI) have developed six ...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 228 million individuals and claimed 4.69 million lives as of Sept 21, 2021. SARS-CoV-2 infects host cells by the ...

A “humanized” mouse model equipped with the immune system of a patient who needs an organ transplant beats current measures for identifying the best potential living donor, scientists report. The ...

A 'humanized' mouse model equipped with the immune system of a patient who needs an organ transplant beats current measures for identifying the best potential living donor, scientists report. A ...

Michael Brehm will speak on Wednesday, April 12 at 3:30 p.m. in Coburn G30 and provide an overview of immunodeficient mouse strains for humanization, then focusing on Engraftment of human immune ...

Researchers generate cutting-edge mouse models by engrafting human cells and tissue into the animals to better study the human immune system. Scientists have employed mouse models in immunological ...