Alzheimer’s researchers have long wished for better mouse models. That is now coming true. Scientists at the Jackson Laboratory in Bar Harbor, Maine, are cranking out numerous lines that express ...

With a grant from NIH, the UC Davis Mouse Biology Program aims to create lab mice with aspects of the human immune system that allow them to support growth of the AIDS virus, HIV. These mice could be ...

Researchers generate cutting-edge mouse models by engrafting human cells and tissue into the animals to better study the human immune system. Scientists have employed mouse models in immunological ...

Infectious diseases such as human immunodeficiency virus (HIV) and hepatitis B (HBV) can have severe implications for liver health, and in the worst cases, cause death. While symptoms vary from ...

A new study published in Microbiology Spectrum reports the establishment of a liver-humanized NSG-PiZ mouse model that is fully permissive to hepatitis B virus (HBV) infection. In this model, HBV can ...

Scientists have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19. Scientists at La Jolla Institute for Immunology (LJI) have developed six ...

Animal research models are only as effective as their ability to simulate human disease. Depending on the condition being studied, researchers were at one time limited to available species that could ...

Michael Brehm will speak on Wednesday, April 12 at 3:30 p.m. in Coburn G30 and provide an overview of immunodeficient mouse strains for humanization, then focusing on Engraftment of human immune ...

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling. Scientists at The University of Texas Health Science Center at San Antonio have created ...

The reconstitution of a fully functional human immune system in mouse after engraftment of purified hCD34+ hematopoietic cells provide a unique opportunity to assess the efficacy of new oncology drug ...