Familial hypercholesterolemia (FH) is a genetic disorder characterized by high levels of low-density lipoprotein cholesterol (LDL-C) in the blood, which significantly increases the risk of ...
Familial hypercholesterolemia results from gene ... and premature coronary artery disease. Statins lower plasma cholesterol by upregulating LDL receptor gene expression and are consequently ...
In a new study just published in the European Heart Journal, researchers from Herlev and Gentofte Hospital quantify for the first time how life expectancy and cardiovascular disease in people ...
The firm’s second candidate, VERVE-102, also targets patients with heterozygous familial hypercholesterolemia and premature coronary artery disease. Although it uses the same base-editing ...