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《Rheumatology International》:Safety and efficacy of IL-17 inhibitors in patients with comorbid multiple sclerosis/multiple Sclerosis-like syndrome: a systematic review 【字体: 大 中 小 】 时间:2025年06月04日 ...
两篇Cell齐发:抗感染的细胞因子IL-17还作用于大脑,引发焦虑或促进社交. 来源:生物世界 2025-04-11 11:13. 这两项研究共同表明,免疫系统,甚至单个 ...
来自巴塞罗那生物医学研究所(IRB Barcelona)与国家基因组分析中心(CNAG)合作的一组科学家发现,IL-17蛋白在皮肤老化中起着核心作用。这项研究由巴塞罗那IRB的Guiomar Solanas博士、Salvador Aznar Benitah博士和CNAG的Holger Heyn博士领导,强调了Il -17介导的衰老过程到炎症状态。
通过对修复相关的淋巴细胞进行无偏见的分析,这些作者发现了17型淋巴细胞的异质性群体的富集。缺少RORγt+细胞的纯合子Rorgt-EGFP小鼠(下称GFI-KI小 ...
礼来IL-23单抗头对头击败乌司奴单抗。 2024年10月14日,礼来更新了旗下IL-23单抗mirikizumab(米吉珠单抗)治疗中重度克罗恩病(CD)患者的三期VIVID-1 ...
本研究是首个银屑病领域在il-17单抗应答不佳人群中开展转药治疗的随机、双盲、活性对照的iii期临床研究,在il-17单抗继续治疗对照下,证明匹康奇 ...
阻断il-17介导的信号通路,可以缓解年老小鼠的年龄相关皮肤炎症,并改善老化皮肤的特征。 皮肤作为我们身体最外层的保护屏障,承受了时间的 ...
Researchers have found in a recent analysis reveals IL-17 inhibitors significantly increase the risk of Candida infections ...
Although TNF inhibitors remain the first choice biologic for many rheumatologists treating psoriatic arthritis, interleukin-17 inhibitors may soon overtake them, according to a market analysis ...
Interleukin-17 and IL-23 inhibitors do not increase the risk for tuberculosis reactivation among patients with psoriatic disease who have a latent tuberculosis infection, according to a ...
Interleukin-17 (IL-17) inhibitors demonstrated faster psoriasis (PsO) clearance than Interleukin-23 (IL-23) inhibitors. However, IL-23 inhibitors were often favored due to their safety profile and ...
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