该研究证实，IL17REL编码一种诱饵受体，能够结合白细胞介素-17（IL-17）家族细胞因子并抑制肠道炎症。 IL17REL基因位点与炎症性肠病（IBD）的易感性相关。然而，该基因是否编码功能性蛋白及其IBD风险变异是否在疾病发病机制中起因果作用，目前尚不清楚。 2026年1月6日，中国科学院上海营养与健康研究所钱友存和杨涛共同通讯在Nature Immunology 在线发表题为The IL1 ...

In a study published in Nature Immunology on January 6, a research team led by Prof. Qian Youcun from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences ...

Increasing evidence suggests that IL-17A and Th17 cells play a major role in autoimmune inflammation, but there are gaps in our understanding of IL-17RA signaling mechanisms. IL-17RA is expressed in ...

A research team led by Prof. QIAN Youcun from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences identified a new member of the human IL-17 receptor ...

A case-time-control study found no association between the initiation of interleukin 17 (IL-17) receptor A inhibitors and major adverse cardiovascular events (MACEs). Researchers conducted a case-time ...

The family of interleukin-17 (IL-17) includes six molecules that respond to infection, in addition to participating in various physiological and pathological processes. A new paper in Signal ...

This new article publication from Acta Pharmaceutica Sinica B, discusses cancer immunotherapy with enveloped self-amplifying mRNA CARG-2020 that modulates IL-12, IL-17 and PD-L1 pathways to prevent ...

Beijing Innocare Pharma Tech Co. Ltd. and Innocare Pharma Ltd. have identified compounds acting as interleukin-17A (IL-17A)/interleukin-17 receptor A (IL-17RA) interaction, interleukin-17A/A (IL17A/A) ...

Immune molecules called cytokines play important roles in the body's defense against infection, helping to control inflammation and coordinating the responses of other immune cells. A growing body of ...