Increasing evidence suggests that IL-17A and Th17 cells play a major role in autoimmune inflammation, but there are gaps in our understanding of IL-17RA signaling mechanisms. IL-17RA is expressed in ...

In a study published in Nature Immunology on January 6, a research team led by Prof. QIAN Youcun from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences ...

The family of interleukin-17 (IL-17) includes six molecules that respond to infection, in addition to participating in various physiological and pathological processes. A new paper in Signal ...

A case-time-control study found no association between the initiation of interleukin 17 (IL-17) receptor A inhibitors and major adverse cardiovascular events (MACEs). Researchers conducted a case-time ...

Neurons (green) in a mouse brain have a receptor (cyan) that detects the immune molecule IL-17. Researchers at Washington University School of Medicine in St. Louis have discovered that a molecule ...

Beijing Innocare Pharma Tech Co. Ltd. and Innocare Pharma Ltd. have identified compounds acting as interleukin-17A (IL-17A)/interleukin-17 receptor A (IL-17RA) interaction, interleukin-17A/A (IL17A/A) ...

Immune molecules called cytokines play important roles in the body's defense against infection, helping to control inflammation and coordinating the responses of other immune cells. A growing body of ...

Targeting multiple immune mechanisms may overcome therapy resistance and further improve cancer immunotherapy for humans. The authors of a new article published in Acta Pharmaceutica Sinica B describe ...

NEWARK, CA / ACCESSWIRE / November 21, 2024 / Protagonist Therapeutics, Inc. ("Protagonist" or the "Company") today announced the selection of PN-881, a potential best-in-class oral peptide ...