肝细胞癌（Hepatocellular carcinoma, HCC）是全球第三大癌症死因，免疫检查点抑制剂（Immune checkpoint inhibitors, ...

This Research Topic is Volume II of a series. The previous volume, which has attracted over 21k views can be found here: New Tumor Immune Checkpoints and ...

Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...

Cancer immunotherapy has transformed modern oncology by harnessing body's own immune system to combat malignant disease.

Two decades after a breast cancer vaccine trial, every participant is still alive—an astonishing result for metastatic ...

Three years after enrolling its first patients, a consortium of researchers examining the growing issue of immune-related adverse events due to immune checkpoint inhibitor cancer therapy released a ...

Cancer immunotherapy has been a game-changer, but many tumors still find ways to slip past the immune system. New research ...

Degrader of cancer protein IDO1 prevents cancer immune suppression by cancer and offers promising strategy to support ...

A study has revealed why some patients don't respond to immune checkpoint blockade (ICB) therapy for solid cancer tumors and identifies a new combination treatment. Publishing in Nature Immunology, ...

In patients who developed cutaneous immune-related adverse events, researchers compared outcomes for those who received ...