Two separate accidents on I-64 have caused major delays.

Three lanes of westbound Interstate 64 are blocked after a reported crash near Louisville Slugger Field Jan. 27, according to ...

One person was killed in a multi-vehicle crash on Interstate 64 in Henrico when a vehicle rolled over Sunday night, according ...

ST. LOUIS — Road construction in the St. Louis region is set to increase as MoDOT and IDOT crews take advantage of calmer winter weather to resume major improvement projects. Lane closures are ...

A bicyclist who appears to have taken a very wrong turn was escorted by police off of Interstate 64 near Forest Park after ...

Parts of I-64 in Shelby County will be closed as crews demolish the KY 53 bridge. Expect detours and delays.

You can add Saint Louis University to the list of organizations and business owners speaking out against the Missouri Department of Transportation plan to rip out the Compton/I-64 interchange. In a ...

NORFOLK, Va. — Motorists can expect delays on Interstate 64 in Norfolk due to a vehicle crash Wednesday. The crash happened at mile marker 283.8 near the I-264 interchange. All eastbound lanes are ...

Overnight ramp closures were scheduled last week to implement the shift.