By combining two fundamentally different microscopy techniques, researchers can now measure the optical properties of a ...

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a single-step technique for ...

Light-sheet microscopy has emerged as a transformative imaging modality that enables rapid, three‐dimensional visualisation of biological specimens with minimal photodamage. By illuminating samples ...

Light microscopy is a cornerstone in life sciences technology, having experienced considerable diversification since its inception. This development becomes visible when considering the distinctive ...

Researchers at Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) have developed an innovative microscopy ...

Assistant Professor of Biomedical Engineering Yi Xue works on 2P-FOCUS, a new two-photon microscopy system, in her lab. The system promises novel insights into biological features that were once only ...

The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

Materials scientists can learn a lot about a sample material by shooting lasers at it. With nonlinear optical microscopy—a specialized imaging technique that looks for a change in the color of intense ...

It is the computational processing of images that reveals the finest details of a sample placed under all kinds of different light microscopes. Even though this processing has come a long way, there ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...