Salk Institute scientists discovered that bile acids in the liver can weaken immune cell function, making immunotherapy less effective against liver cancer. They pinpointed specific bile acids that ...

Figure 1 BET inhibition is synthetic lethal to OXPHOS blockage in liver cancer. Left: GDH1-dependent glutamine metabolic remodeling upon BET inhibition. Right: “Synthetic lethality” targeting OXPHOS ...

David Pellman (left) is a professor at the Dana-Farber Cancer Institute and Harvard Medical School (both MA, USA), who also has affiliations with Howard Hughes Medical Institute (MD, USA) and the ...

A new study examines the effects of cancer and its treatment on the aging process. Investigators found that expression of a gene associated with aging is higher in young patients with cancer after ...