This webinar explores how liver microphysiological systems support toxicology from early screening to species-specific risk ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

The effectiveness of non-clinical drug safety predictions is enhanced by the adoption of three-dimensional (3D) cellular models. 3D bioprinting enables the generation of complex models with spatial ...

The connection between the human liver and the intestine is unique, and the “gut-liver axis” plays a vital role in regulating liver disease pathology. When homeostasis is disturbed, changes in dietary ...

Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have helped to understand liver biology, they often fail to accurately ...

Using human induced pluripotent stem cells, researchers have built a miniature 3D liver model that replicates the critical interaction between hepatocytes and stellate cells. As chronic liver disease ...

ROCHESTER, Minn. — As rates of obesity, high blood pressure, type 2 diabetes and sleep apnea increase, cases of advanced chronic liver disease and resulting liver scarring or cirrhosis also are rising ...

Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have helped to understand liver biology, they often fail to accurately ...

Adoption of a new version of the Model for End-Stage Liver Disease, known as MELD 3.0, closed the gap in access to liver transplant between men and women, an analysis showed. Since MELD 3.0 was ...

"As a family physician, I've often seen how advanced liver disease — which frequently has no symptoms until it becomes irreversible — can go undetected," says David Rushlow, M.D., Mayo Clinic Health ...