We previously demonstrated that the up-regulation of p53, Fas, and DNA damage are present in lung epithelial cells from patients with idiopathic interstitial pneumonias (IIP). Fas ligation induces ...

In the autopsy lung samples, apoptosis was detected mainly (>90%) in the epithelial cells, confirmed with TUNEL, MNF-116, and M30 stainings (Figs. 1 and 2).The number of apoptotic epithelial cells ...