Fibroblastic reticular cells (FRCs) are heterogeneous stromal cells. Subsets of FRCs include: T cell zone reticular cells that produce interleukin-7 (IL-7) to support naive T cells; resident and ...

The lymphatic system is basically a channel that carries a clear or whitish fluid called the lymph. This lymph aids in clearing the tissues of infective organisms, toxins etc. The basic structure and ...

Swollen lymph nodes, or swollen glands, in the neck may indicate an infection. They can also occur due to a medical condition, such as an immune disorder or, less commonly, cancer. Treatment can ...

A new study from researchers at Uppsala University presents novel findings on why human lymph nodes lose their function with age and the consequences for the effectiveness of our immune system. The ...

Figure 1: Access to SLOs is important for maintenance of the peripheral T cell pool. Figure 3: The gp38 + CD31 − FRCs are the main source of IL-7 in naive lymph nodes. Figure 5: TRCs support the ...

Systemic therapy for sarcoidosis is reserved for organ-threatening disease, and laryngeal involvement necessitates treatment ...

The frequent spread of certain cancers to lymph nodes often necessitates surgery or radiation therapy that damages the lymphatic system. The new study demonstrate for the first time that growth factor ...

If we imagine our immune system to be a police force for our bodies, then previous work has suggested that the Lymph nodes would be the best candidate structures within the body to act as police ...

These findings from research into diffuse large B cell lymphoma (DLBCL) are based on analyses of human patients and a murine model. The immunosuppressive role of fibroblastic reticular cells (FRCs) in ...

If we imagine our immune system to be a police force for our bodies, then previous work has suggested that the Lymph nodes would be the best candidate structures within the body to act as police ...

If we imagine our immune system to be a police force for our bodies, then previous work has suggested that the Lymph nodes would be the best candidate structures within the body to act as police ...