直接MALDI-TOF MS快速鉴定病原体在血液等无菌体液中的应用研究，发现其可在30-60分钟内完成病原体鉴定，但存在革兰氏阴性菌识别率高于阳性菌及真菌的现象，主要受样本中微生物浓度、细胞壁结构及蛋白质提取效率影响，同时面临低灵敏度样本、基质干扰、多 ...

艰难梭菌（Clostridioides difficile）感染（CDI）是最常见的医疗相关感染之一，导致显著的发病率和死亡率。CDI的诊断需要临床评估和实验室检测。本研究旨在评估MALDI-TOF质谱技术在识别产毒艰难梭菌菌株方面的有效性。 方法 从2019年5月到2024年3月，所有通过PCR检测 ...

Homology surveillance of carbapenem-resistant Klebsiella pneumoniae (CRKP) is critical to monitor and prevent outbreaks of nosocomial infections. In the present study, a matrix-assisted laser ...

Bruker Corporation BRKR recently announced the launch of the neofleX Imaging Profiler for mass spectrometry-based tissue imaging at the 72nd ASMS meeting. The novel, high-performance MALDI-TOF/TOF ...

MALDI-TOF MS yields absolute molecular weights not relative ones. MALDI-TOF MS is a fast and versatile method to address challenges in the synthesis or quality control of polymers. Structural features ...

The inimitable adaptability of MALDI-TOF/TOF systems enables tissue imaging of intact proteins, as well as of tryptic peptides brought about by on-tissue digestion. Although intact protein imaging can ...

It's been 20 years since Hillenkamp and Karas developed MALDI. In that time, the soft ionization method, coupled with time-of-flight (TOF) mass spectrometry, has distinguished itself as the enabling ...

neofleX is a versatile, high-performance, and easy-to-use multiomics MSI system for biopharma, translational and clinical researchers neofleX Imaging Profiler MALDI-TOF/TOF with proprietary smartbeam ...