Dysfunction of autophagy in plaque macrophages aggravates atherosclerosis. Here the authors show that induction of macrophage autophagy–lysosomal biogenesis either genetically by overexpression ...

MACROPHAGE AUTOPHAGY: The autophagosomes within macrophages helps keep atherosclerotic plaques from bursting and causing blood clots. KRISTY BROWN AND YING WANG, COLUMBIA UNIVERSITY X. Liao et al., ...

Learning Objectives: 1. Understand the use of flow cytometry-based medium throughput screening assays as an essential tool to investigate macrophage phagocytosis 2. Describe the role of pSTAT3 as a ...

This review discusses the cellular process of autophagy (“self-eating”), which plays key roles in normal development of the immune system and adaptation to stress, as well as in a wide range ...

Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells. It allows your body to remove the dysfunctional cells.

Recycling takes place in our cells at all times: in a process called autophagy, cell components that are no longer needed are enclosed by membranes and broken down into their basic building blocks.

Autophagy may be Nobel-winning research, but so far there’s no evidence that boosting how your cells recycle nutrients makes you live longer or lose weight.

Role of PI3K/Akt/mTOR pathway-mediated macrophage autophagy in affecting the phenotype transformation of lung fibroblasts induced by silica dust exposure ...

Cell biologist Yoshinori Ohsumi wins the 2016 Nobel Prize in physiology or medicine for discoveries in autophagy. Wait, what's autophagy?

Resolution Therapeutics Announces Regenerative Macrophage Therapy (RMT) Manufacturing Process & Candidate Testing Suite at ASGCT 2025 – Proprietary manufacturing process enables robust and scalable ...

Autophagy is a complex process of intracellular degradation of senescent or malfunctioning organelles. Dysregulated autophagy is associated with certain cancers, neurodegenerative diseases, immune ...