Dysfunction of autophagy in plaque macrophages aggravates atherosclerosis. Here the authors show that induction of macrophage autophagy–lysosomal biogenesis either genetically by overexpression ...

This review discusses the cellular process of autophagy (“self-eating”), which plays key roles in normal development of the immune system and adaptation to stress, as well as in a wide range ...

MACROPHAGE AUTOPHAGY: The autophagosomes within macrophages helps keep atherosclerotic plaques from bursting and causing blood clots. KRISTY BROWN AND YING WANG, COLUMBIA UNIVERSITY X. Liao et al., ...

Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells. It allows your body to remove the dysfunctional cells.

Learning Objectives: 1. Understand the use of flow cytometry-based medium throughput screening assays as an essential tool to investigate macrophage phagocytosis 2. Describe the role of pSTAT3 as a ...

Role of PI3K/Akt/mTOR pathway-mediated macrophage autophagy in affecting the phenotype transformation of lung fibroblasts induced by silica dust exposure ...

Autophagy may be Nobel-winning research, but so far there’s no evidence that boosting how your cells recycle nutrients makes you live longer or lose weight.

Clinical trials involving patients with relapsed/refractory HRNB have demonstrated encouraging response rates to treatment with the anti-GD2 antibody dinutuximab with irinotecan, temozolomide, and ...