Many powerful genome editing approaches must create breaks across both strands of the DNA double helix and rely on the cell’s own DNA repair machinery to introduce desired changes in the sequence. If ...

Scientists at the University of North Carolina School of Medicine and UNC Lineberger Comprehensive Cancer Center say they have developed a technique for finding where DNA repair happens throughout all ...

When common chemotherapy drugs damage DNA in cancer cells, the cells can't replicate. But the cells do have ways to repair the DNA and the cancer drugs aren't effective to do so. Researchers have ...