The process of DNA replication is highly conserved throughout evolution. Investigating the replication machinery in simple organisms has helped tremendously to understand how the process works in ...

There is still much to be learned concerning the mechanisms of translocation ... all aspects of nucleic acid metabolism, ranging from DNA replication to chromatin remodelling.

We are interested in the mechanism of chromosome replication, a process that is highly conserved across eukaryotes and that involves the duplication of both the chromosomal DNA and its associated ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

2019), suggesting the replication and reassembly of nucleosomes at telomeres occurs through a distinct mechanism. The successful candidate will examine this mechanism using a combination of ...

DNA replication, repair, and damage response ... to developmental disorders such as diabetes and premature aging. Our lab investigates 3R mechanisms, 3R protein functions and structures, and their ...

This process is essential for the proper functioning and survival of all living organisms. DNA replication is the process by which the DNA molecule makes an exact copy of itself during cell division.

A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged.

which is crucial for us to understand the molecular mechanism of DNA replication," said Dr. Shangyu Dang, Assistant Professor of Division of Life Science, HKUST, "This study also demonstrates the ...

We also discovered that this breakage mechanism only occurs at the beginning of the cell cycle phase, when DNA replication ...

For example, the act of copying and reading DNA overwinds it ahead of the enzymes that read and copy the genetic code, ...