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生物通
6 个月
Merlin缺陷型肾细胞癌:基于NF2/merlin免疫组化与分子特征的高级别实体 ...
来自国际研究团队的最新研究揭示了NF2突变肾肿瘤的分子特征与形态学谱系。通过14例NF2突变肿瘤的综合分析,研究者证实merlin(NF2编码蛋白)免疫组化可作为诊断标志物,首次提出"merlin缺陷型RCC"概念——这类高级别肿瘤具有特征性嗜酸性细胞学、间质硬化及NF2 ...
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