The production of butanediol – notably 2,3-butanediol – has emerged as a pivotal area in industrial biotechnology owing to its extensive applications in fuel additives, polymer synthesis and chemical ...

In silico analysis of five industrial microorganisms identifies optimal strains and metabolic engineering strategies for producing 235 valuable chemicals. Climate change and the depletion of fossil ...

Metabolic engineering of Corynebacterium glutamicum has long been a cornerstone of industrial biotechnology, contributing greatly to the bio‐based production of essential amino acids. Over recent ...

The mitochondrion, often referred to as the powerhouse of the cell, plays critical roles in cellular function, making it a prime organelle to target for fundamental studies, metabolic engineering, and ...

Free-energy (ATP) conservation during product formation is crucial for the maximum product yield that can be obtained, but often overlooked in metabolic engineering strategies. Product pathways that ...

Sulfolobus islandicus, an archaeal model organism, offers unique advantages for metabolic engineering and synthetic biology ...

In this study, a principle of cancer cell metabolism was elucidated by integrating 13 C-metabolic flux analysis with flux balance analysis. The findings reveal that glycolysis-dependent, less ...

(Nanowerk News) Metabolic engineering has enabled the construction of efficient microbial cell factories, but cellular aging and the accumulation of toxic metabolites during prolonged fed-batch ...

This review synthesizes progress in pathway optimization, regulatory rewiring, and microbial cell factory design that has ...