Pattern of response to antidepressants has been proposed as a method to identify patients whose improvement is more likely due to drug vs those whose improvement on drug is more likely to be a placebo ...

Mirtazapine is a central alpha-2 antagonist currently FDA-approved for the treatment of major depressive disorder. The antidepressant mirtazapine appears to be a safe and effective treatment option ...

Patients with depression who were prescribed mirtazapine or venlafaxine as a second-line antidepressant had a higher rate of serious self-harm than those who were prescribed a selective serotonin ...