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Mutation To Mismatch Repair Gene Associated With Colorectal Cancer. ScienceDaily. Retrieved June 4, 2025 from www.sciencedaily.com / releases / 2007 / 03 / 070321161840.htm.
An analysis of how regional mutation rates vary across 652 tumours identifies variable DNA mismatch repair as the basis of the characteristic regional variation in mutation rates seen across the ...
Pathogenic somatic mutation (SM) of mismatch repair (MMR) genes and associations with microsatellite instability (MSI), tumor mutational burden (TMB) and SM in other DNA repair pathways in 24,223 ...
This is an archived article and the information in the article may be outdated. Please look at the time stamp on the story to see when it was last updated. Flu season may be especially bad over ...
We identified a mean of 578 potential mutation-associated neoantigens from the tumors of patients with mismatch repair–deficient cancers; 21 such neoantigens were identified in tumors from ...
Metachronous colorectal cancer in mismatch repair gene mutation carriers: The advantage of more extensive surgery.. JCO 28 , 3515-3515 (2010). DOI: 10.1200/jco.2010.28.15_suppl.3515 ...
The 2014-2015 flu vaccine didn't work as well compared to previous years because the H3N2 virus recently acquired a mutation that concealed the infection from the immune system. A study published ...
Up to 15 percent of colorectal cancers show a genetic mutation known as DNA mismatch repair deficiency, or dMMR. Until now, little has been known about how the mutation behaves in rectal cancer ...
Mismatch repair deficiency refers to a characteristic of some cancer cells that create ... a well-known biomarker that can be used in a new way. This biomarker isn’t a particular genetic mutation.
This mismatch occurs in the process of replicating DNA, which begins when the two strands unzip. A protein enzyme called DNA polymerase then works its way along one "template" strand adding ...
The flu vaccination doctors created for this season, the 2021-2022 Northern Hemisphere influenza vaccine, appears to do a poor job of neutralizing this particular mutation of H3N2.