2 The team fused DAAO to either a nucleosome protein or a mitochondrial membrane protein to study the effects of hydrogen peroxide produced at these specific locations. The team hypothesized that ...
Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant ...
In the past 13 years, more than 100 point mutations and innumerable rearrangements of mitochondrial DNA (mtDNA) have been associated with human mitochondrial disease. In the past five years ...
为探究肝癌(HCC)对索拉非尼耐药机制,研究人员开展相关研究,发现循环线粒体 DNA 促进 M2 型肿瘤相关巨噬细胞(TAMs)极化及肝癌耐药,为治疗提供新策略。
DNA is susceptible to damage caused by errors committed during replication and by environmental ... Ligase IIIa is expressed ubiquitously and is implicated in DNA repair and is essential for ...
12 天
News-Medical.Net on MSNTargeting mitochondrial DNA integrity for cardiac protection after injuryMaintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant ...
10 天
News Medical on MSNHow tobacco and cannabis affect male fertility and genetic integrityA study reveals cannabis and tobacco use harm sperm quality and DNA integrity, with cannabis causing greater damage, raising ...
As the mitochondrial lingo gets a makeover, so do some longstanding beliefs about this organelle. For example, Tobias Dansen and Daan van Soest at the University Medical Center Utrecht tackled the ...
Melatonin supplementation may help offset the DNA damage associated with night shift work by boosting the body's ability to repair it, suggest the findings of a small clinical trial published ...
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