Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...

ATAD3A is a mitochondrial membrane-bound ATPase that is emerging as a central regulator of mitochondrial dynamics and structural integrity. It plays a critical role in organising the inner ...

Mitochondrial dynamics, governed by the interplay of fission and fusion proteins, are essential for maintaining cellular function and homeostasis. Fission facilitates glycolysis, mitophagy, apoptosis, ...

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin sensitivity in patients with Type 2 Diabetes, ...

Researchers at The Wistar Institute have identified a previously unknown mechanism by which viruses can reprogram mitochondrial structure to silence immune responses and ensure successful viral ...

Mitochondrial dysfunctions are associated with a variety of pathologies, and the onset and progression of disease are accompanied by alterations in extracellular biochemical and mechanical signals.

Mitochondria have long been known as the tiny organelles that act as the battery packs inside our cells while also serving as internal sensors and communicators. But relatively little is understood ...